GENETIC POLYMORPHISM OF SERUM ALBUMIN IN THE CARPATHIAN BREED IN ECONOGENIC INTERRELATION WITH OTHER GOAT BREEDS
Gh. Hrincă
Abstract
This paper has proposed to reveal the albumin polymorphism in goats belonging to the Carpathian breed. Identification of albumin phenotypes was performed from blood serum of animals by starch gel electrophoresis method. Depending on the migration speed of albumin fractions, three phenotypes were found: homotype AlbFF (with fast electrophoretic migration), homotype AlbSS (with slow electrophoretic migration) and heterotype AlbFS (with intermediate electrophoretic migration). Emergence of albumin phenotypes is due to the two co-dominant autosomal alleles, AlbF si AlbS, whose distribution is unequal within the population, the allele AlbS being very common (83.66%) compared to allele AlbF (16,34%). Unequal spread of these alleles causes a differentiated distribution of albumin genotypes: homozygotes AlbSAlbS are the most common (70.24%), heterozygotes AlbFAlbS are enough well represented (26.83%), and homozygotes AlbFAlbF register a very low frequency (2.93%). As a result, the summed homozygosity (AlbFAlbF + AlbSAlbS is three times more frequent (73.17%) than heterozygosity AlbFAlbS (26.83%). The Carpathian breed is in Hardy-Weinberg genetic equilibrium at the locus Alb, both at the level of individual albumin genotypes, as well as regarding the general status of albumin zigosity. From the econogenic point of view, the Carpathian breed is similar to several breeds of goats of the Central and Eastern Europe.
Key words: albumin, genetic polymorphism, goat
POLIMORFISMUL GENETIC AL ALBUMINEI SERICE LA RASA CARPATINĂ IN INTERRELAŢIONARE ECONOGENETICĂ CU ALTE RASE DE CAPRINE
Gh. Hrincă
Rezumat
Lucrarea si-a propus evidentierea polimorfismului albuminic la caprele din rasa Carpatina. Identificarea fenotipurilor albuminice s-a realizat din serul sanguin al animalelor prin metoda electroforezei în gel de amidon. În functie de viteza de migrare a fractiunilor albuminice, s-au gasit trei fenotipuri: homotipul AlbFF (cu migrare electroforetica rapida), homotipul AlbSS (cu migrare electroforetica lenta) si heterotipul AlbFS (cu migrare electroforetica intermediara). Aparitia fenotipurilor albuminice se datoreaza celor doua alele codominante autozomale, AlbF si AlbS, a caror raspândire este inegala în cadrul populatiei, alela AlbS fiind foarte frecvent întâlnita (83,66%) în comparatie cu alela AlbF (16,34%). Raspândirea inegala a acestor alele determina o distributie diferentiata a genotipurilor albuminice: homozigotii AlbSAlbS sunt cel mai des întâlniti (70,24%), heterozigotii AlbFAlbS sunt destul de bine reprezentati (26,83%), iar homozigotii AlbFAlbF înregistreaza o frecventa foarte slaba (2,93%). Ca urmare, homozigotia însumata (AlbFAlbF + AlbSAlbS este de trei ori mai frecventa (73,17%) decât heterozigotia AlbFAlbS (26,83%). Rasa Carpatina se afla în echilibru genetic Hardy-Weinberg la locus-ul Alb, atât la nivelul genotipurilor albuminice individuale, cât si în ceea ce priveste status-ul zigotiei albuminice generale. Sub aspect econogenic, rasa Carpatina este similara câtorva rase de caprine din Centrul si Estul Europei.
